The accuracy of subjective reports, especially those involving introspection of one’s own internal processes, remains unclear. ‘Introspective accuracy’ (IA) can putatively be quantified by a variety of methods that combine introspective reports of subjective, mental phenomena with some objective (neural, physiological, or behavioral) measure of these same phenomena. A subject’s IA with respect to a …
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The effect of MBSR on episodic and prospective memory function in aging adults
Mild cognitive impairment (MCI) is a state of cognitive decline between typical aging and dementia characterized by impaired memory function, particularly for episodic memory—the capacity to mentally relive past experiences—and prospective memory—the ability to recollect future intentions. People diagnosed with MCI are 20-50% more likely to develop dementia over a period of 2 to 3 …
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A longitudinal training study to delineate the specific causal effects of open monitoring versus focused attention techniques on emotional regulation skills
Difficulties with emotion regulation could be a core mechanism of mood and anxiety disorders. Various meditation-based interventions are found to ameliorate a wide range of psychological problems however, it is crucial to understand how different types of meditation improve emotional abilities to develop structured treatment and preventative protocols for emotional disorders. Based on a commonly …
Neural effects of Mindfulness-Based Cognitive Therapy in remitted patients with chronic history of depression
Clinical evidence suggests that MBCT is an effective intervention to prevent relapse in major depression. The mechanisms underlying the positive effects of Mindfulness-Based Stress Reduction on different forms of human suffering have been studied extensively in healthy populations. However, little has been done to extend this research to study the neural and psychological mechanisms underlying …
Making the right choice: Combining neuroimaging, computational modelling, and first-person report methodologies to unveil neural mechanisms of human flourishing
While the combined use of computational modelling and experimental techniques in neuroscience has been fruitful for studying decision-making, it has mostly focused on general principles of reward-based decision-making and has not been utilized to examine wider implications for human well-being. On the other hand, the emerging field of positive psychology has provided a framework for …
Mechanisms of Meditation and Consequences for Clinical Practice
Mindfulness and meditation are increasingly used in clinical practice to treat conditions such as depression, anxiety and addiction. However, the fundamental mechanisms underlying these practices are not yet well-known and theoretical frameworks are sparse. Two important explanatory mechanisms that will be considered in this workshop are sticky thinking (cognitive fusion) and the sense of self. …
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Core Measures for Mindfulness Studies
We aim to develop a set of recommended “core measures” for mindfulness-based intervention research that can strengthen individual studies and facilitate pooled data analyses and meta-analyses. While most studies require study specific outcome measures, there are domains that are appropriate to measure across studies. These includes self-report measures of important common outcomes (e.g. stress and …
Microphenomenology and Contemplative Experience: Exploring the Intra- and Intersubjective Dynamics of Language and Embodied Experience
We will host a two-day meeting of scholars from the humanities and sciences and contemplative practitioners to explore and develop the use of microphenomenology in the study, practice and application of contemplative practice. The meeting will bring together core members of the PhenoPilot project, with a small group of other scholars and practitioners in order …
Intrinsic neural characteristics predict the effectiveness of MBSR training on fear extinction and stress reduction
The proposed research aims to derive individual neural characteristics from data-driven analysis of resting state fMRI to predict the effectiveness of Mindfulness-Based Stress Reduction (MBSR) training on fear extinction and stress reduction. This project aims to capture the individual variability in the amplitudes of spontaneous brain activity and neural network properties, and relate such variability …
Can supercharged memory consolidation during sleep boost compassion and pro-sociality?
Recent advances in memory research indicate that cognitive processing during sleep supports memory storage (e.g., Paller & Voss, 2004; Born, 2010). In recent studies from our lab, individual memories were strengthened through memory reactivation achieved by presenting task-associated sounds during sleep (Rudoy et al., 2009; Creery et al., in preparation). Here, we propose to use …

