A considerable number of those who suffer from depression develop a chronic course of the disorder in which symptoms remain over prolonged periods of time and risk for suicidality is significantly increased. Once patients have entered such a course, response to established treatments is significantly reduced. The aim of the current study was to test …
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Neural Correlates of PTSD Prevention with MBSR in Iraq Veterans
With recently discharged veterans from Operation Iraqi Freedom (OIF) as our subjects, this study examines the neuroanatomical underpinnings as well as cognitive and perceptual biases associated with the progression of early onset Posttraumatic Stress Disorder (PTSD). We are comparing the efficacy of Mindfulness-Based Stress Reduction (MBSR; treatment) to Supportive Therapy (ST; control) as early interventions …
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Mindfulness-based interventions for depression: Possible neurophysiological mechanisms
Previous studies have indicated that mindfulness and other forms of meditation training are associated with improvements in sleep quality. However, none of these studies used objective polysomnographic sleep recordings. The aim of this study was to examine whether mindfulness meditation was associated with improvements in objectively measured sleep, according to polysomnography (PSG), and to relate …
Establishing mindfulness and mind wandering as mediators of patient benefit in MBCT
Prior studies have focused on the impact of mindfulness-based interventions on alleviating physical or psychological symptoms or difficulties (e.g., Teasdale et al., 2000; Ma & Teasdale, 2004), or on enhancing positive states, including mindfulness itself (E.g., Brown & Ryan, 2003). Relatively little work has focused on cognitive measures that might reflect the presence or absence …
Feasibility, clinical acceptability, and efficacy of a mindfulness-based group therapy intervention for PTSD
Posttraumatic stress disorder (PTSD) is seriously debilitating and common, with 5-10% incidence in general population and over 30% in combat veterans. PTSD symptoms include emotional dysregulation, intrusive, distressing trauma memories, nightmares, and ‘flashbacks’. Our laboratory has reported exaggerated a.) first-person emotional b.) psychophysiological and c.) neuroendocrine responses to trauma recall in combat PTSD patients, and …
Effectiveness of the Mindfulness Education Program on children’s social-emotional competence, psychological well-being, and stress reactivity
The objective of present study is to evaluate the effectiveness of a primary prevention program—“Mindfulness Education” (ME)—a classroom-based program designed to foster children’s mindful awareness, psychological well-being, and social-emotional competencies. This study will provide an examination of multiple areas of functioning—cognitive, affective, behavioural, interpersonal and physiological through the collection of data from multiple-informants (self-reports, peer …
Fellow Spotlight: Norm Farb
In this month’s Fellow Spotlight we are pleased to share the work of Norman Farb, Associate Professor of Psychology and Principal Investigator of the Regulatory and Affective Dynamics Laboratory at the University of Toronto Mississauga. Norm studies the social neuroscience of the self and human emotion, with a focus on how biases in self-representation shape emotions to determine …
Varieties of Contemplative Experience
The Contemplative Development Mapping Project (CDMP) is a group of scholars, scientists, and practitioners who are personally and professionally committed to enriching our understanding of contemplative practices and experiences. This interdisciplinary “think tank” is comprised of researchers from a range of disciplines, including philosophy, sociology, psychiatry, psychology, neuroscience and religious studies. By integrating first-person, second-person, …
Mindfulness-based interventions for depression: Possible neurophysiological mechanisms
Previous studies have indicated that mindfulness and other forms of meditation training are associated with improvements in sleep quality. However, none of these studies used objective polysomnographic sleep recordings. The aim of this study was to examine whether mindfulness meditation was associated with improvements in objectively measured sleep, according to polysomnography (PSG), and to relate …
Mindfulness meditation for social anxiety disorder: Examining the neural and psychological mechanisms of therapeutic change
There is a growing interest in the application of mindfulness techniques for modulating one’s relationship to ongoing mental experience. However, there is need for detailed empirical investigations using experimental paradigms to address (a) whether mindfulness training works, (b) how it affects emotional reactivity and regulation, (c) what neural systems are modulated by training in mindfulness …

