Few randomized controlled trials have directly compared the effects of mindfulness and acceptance-based MBSR and reappraisal-based CBT in the treatment of anxiety disorders. In the current study, we propose a randomized pilot study that compares MBSR and group CBT to enable a direct assessment of training in reappraisal and mindfulness-based emotion regulatory strategies, and their …
Grant Type Archives:
Effects of mindfulness meditation on cell aging processes
Chronic stress and major depressive disorder are associated with accelerated cellular aging, indicated by shortened telomeres in peripheral blood mononuclear cells (PBMCs). Psychological distress is also related to greater oxidative stress, a known cause of telomere shortening. The primary aim of the proposed research is to determine whether mindfulness meditation reduces oxidative stress and increases …
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Biopsychosocial assessment of a mindfulness-oriented treatment of alcohol dependence
This project will investigate the feasibility, acceptability, effect sizes, and therapeutic mechanisms of a novel, mindfulness-oriented cognitive therapy (MOCT) intervention for alcohol dependence, focusing on how attentional processes impact craving. A randomized control group design will be used, with 24 adult alcohol dependent persons per group. The MOCT arm will participate in 8 weekly 2 …
A randomized controlled single-blinded pilot trial to compare effects of concentrative sitting meditation to moving meditation (tai chi) training on attentional network efficiency
Meditation training has been shown to positively affect executive attention function. Moderate aerobic exercise has also been shown to improve executive attention function. Tai Chi requires moderate aerobic exertion, is considered a form of moving meditation, and requires motor learning. Motor learning engages executive function. Thus, Tai Chi can be expected to positively affect executive …
Does mindfulness training change the processing of social threat?
Mindfulness training is theorized to lead to a shift in perspective, a so-called “reperceiving”. The observing of inner experiences, thoughts, and emotions leads to a dis-identification from these contents of consciousness, which facilitates exposure and is thought to result in a reduction in emotional reactivity and to more adaptive responding in situations of social threat. …
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Neuropeptide levels in meditation
Mindfulness-Based Stress Reduction (MBSR) or other forms of meditation have been found to decrease blood pressure, improve sleep, decrease anxiety and stress, decrease cortisol, induce the immune response, and produce other health benefits. However, the mechanism of action of meditation’s beneficial effect on health is uncertain. The peptide neurohormone oxytocin is generally considered to have …
The dissolution of self during rhythmic motor behavior
Rhythmic drumming is a common method to induce trance states of consciousness in many cultures around the world. The techniques and drum tempi are highly similar across cultures, and likely developed independently (convergent evolution). In order to study the rhythmic induction of trance, shamanic practitioners with extensive experience using drums to alter consciousness, traveled to …
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MBSR for the treatment of pediatric chronic pain
Pediatric chronic pain is a significant public health problem. MBSR has been used in the treatment of a wide variety of clinical conditions, such as chronic pain, whether MBSR is effective for chronic pain in youth remains an empirical question. The proposed study is a two-arm randomized clinical trial examining MBSR for pediatric chronic pain. …
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Efficacy of a 16-week mindfulness-based group for combat PTSD in recruiting veterans, and pilot effects on threat detection and emotion regulation neurocircuitry
We conducted a pilot study to investigate the feasibility, acceptability, and efficacy of an eight week “mindfulness-based” cognitive behavioral group therapy for chronic combat posttraumatic stress disorder (PTSD). Veterans seeking treatment at a Veterans Administration outpatient PTSD clinic (n=11) were enrolled in the study; five completed all eight sessions, three completed at least six sessions, …
Neural effects of mindfulness training on adults with ADD
In this proposal I seek to shed light on the behavioral and neural effects of mindfulness meditation training (MMT) on attention, memory, and inhibition in adults with attention deficit/hyperactive disorder (ADHD). Eligible subjects who reach criteria for ADHD as per evaluation by the Upenn center of cognitive therapy will attend an 8-week MMT course tailored …
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