Neural effects of Mindfulness-Based Cognitive Therapy in remitted patients with chronic history of depression

Clinical evidence suggests that MBCT is an effective intervention to prevent relapse in major depression. The mechanisms underlying the positive effects of Mindfulness-Based Stress Reduction on different forms of human suffering have been studied extensively in healthy populations. However, little has been done to extend this research to study the neural and psychological mechanisms underlying …

Making the right choice: Combining neuroimaging, computational modelling, and first-person report methodologies to unveil neural mechanisms of human flourishing

While the combined use of computational modelling and experimental techniques in neuroscience has been fruitful for studying decision-making, it has mostly focused on general principles of reward-based decision-making and has not been utilized to examine wider implications for human well-being. On the other hand, the emerging field of positive psychology has provided a framework for …

From intra- to inter-personal: Effects of MBSR on emotion regulation in social contexts

Contemplative teachings highlight the benefit of mindfulness practice to the practitioner and to those with whom they interact, yet very few studies on meditation to date have explored whether meditation training improves social interactions and relationships. Examining effects on emotion regulation in social contexts may be key to understanding meditation’s social consequences, for at least …

Intrinsic neural characteristics predict the effectiveness of MBSR training on fear extinction and stress reduction

The proposed research aims to derive individual neural characteristics from data-driven analysis of resting state fMRI to predict the effectiveness of Mindfulness-Based Stress Reduction (MBSR) training on fear extinction and stress reduction. This project aims to capture the individual variability in the amplitudes of spontaneous brain activity and neural network properties, and relate such variability …

Compassion- and mindfulness-based meditation: Nurturing pro-social behavior and social networks

In previous years, scientists documented many personal benefits resulting from mindfulness- and compassion-based meditation, including increases in health. There was less known, however, regarding the social and relational benefits of meditation. Thus, this project examined whether mindfulness and compassion-based meditation training increased the likelihood that people would act to relieve the suffering of others in …

Can supercharged memory consolidation during sleep boost compassion and pro-sociality?

Recent advances in memory research indicate that cognitive processing during sleep supports memory storage (e.g., Paller & Voss, 2004; Born, 2010). In recent studies from our lab, individual memories were strengthened through memory reactivation achieved by presenting task-associated sounds during sleep (Rudoy et al., 2009; Creery et al., in preparation). Here, we propose to use …

An investigation of the impact of mindfulness training on the development of attention and working memory in children

The PI will recruit a mentor teacher (with a minimum of 5 years of teaching experience and 1 year of practicing mindfulness) from a school where at least 10 classroom teachers are willing to be assigned to a mindfulness or control condition. The mentor teacher will collect data from computerized measures on attention and working …

Effects of open monitoring on visual search: Evidence from eye-tracking, electrophysiology, and phenomenology

Whereas many studies have explored the impact of meditative training on the ability to sustain a narrow attentional focus, few have investigated the impact of such training on the ability to expand the window of attention. The present study will investigate the influence of long-term open-monitoring (OM) practice on visual attention. In line with contemplative …

Brain mechanisms distinguishing mindfulness meditation-related pain relief from placebo analgesia

We will assess if mindfulness-meditation reduces pain above and beyond the indirect effects associated with these constructs by employing robust comparison conditions (i.e., placebo conditioning, active control intervention). The study under proposed fellowship will provide unique insight into the brain mechanisms supporting modulation of pain by mindfulness meditation and placebo conditioning, an important step in …

The eCALM Study: eTherapy for Cancer AppLying Mindfulness

Elevated stress can exacerbate cancer symptom severity, and after completion of primary cancer treatments, many individuals continue to have significant distress. Mindfulness-Based Cancer Recovery (MBCR) is an 8-week group psychosocial intervention consisting of training in mindfulness meditation and yoga designed to mitigate stress, pain, and chronic illness. Efficacy research shows face-to-face (F2F) MBCR programs have …