Non-dual awareness (NDA) has been identified as an important aspect of spiritual awakenings, from contemplative trainings practiced in both traditional wisdom traditions and in emerging contemporary “Dharma” teachings (such as mindfulness-based stress reduction and mindfulness-oriented recovery enhancement). Although NDA itself may not necessarily be an ultimate goal or destination, attaining NDA may signify an important landmark for one’s contemplative development. The purpose of this interdisciplinary panel is to explore the merit of investigating NDA in the context of emerging interdisciplinary contemplative studies. The panel will consider how best to investigate NDA in empirically tractable ways, with four presentations by an interdisciplinary panel consisting of a research psychologist, a Buddhist scholar and contemplative, a neuroscientist, and a translational contemplative clinical scientist. In the end, the panel will open the discussion to the audience, with the hope of identifying other outstanding issues for a better understanding of NDA in contemporary contemplative practice.