Surviving a cancer diagnosis and the treatment that follows requires overcoming significant emotional and physical hurdles. Even after a patient is cancer-free, he or she often continues to struggle with depression and anxiety from fear of cancer recurrence, and many also suffer from sleep disturbances. These ongoing challenges negatively impact well-being and quality of life, hindering a patient’s ability to fully flourish. Might contemplative practices help cancer survivors deal better with their mental and physical challenges to remain cancer free? In a recent study published in Integrative Cancer Therapies, Varela awardee David Lipschitz, MLI Fellow Yoshio Nakamura and colleagues at the University of Utah investigated the effects of two mind-body interventions on a number of physiological and psychological health outcomes in cancer survivors. This study used a strong experimental design, comparing three similar interventions to which participants were randomly assigned: mind-body bridging, mindfulness meditation, and a sleep education group as an active control. Below, David Lipschitz summarizes his Varela research project and its findings.
— Wendy Hasenkamp, Senior Scientific Officer
Mind–Body Interventions Affect Sleep and Oxytocin in Cancer Survivors
by David L. Lipschitz, PhD
Oxytocin is a hormone produced in an area of the brain known as the hypothalamus, whose release activates a variety of brain regions resulting in many different functions, including birth (labor), breast feeding (lactation), maternal behavior, parental care, social bonding, affiliation (such as couples being together), and well-being. In recent studies in humans, oxytocin has been shown to be associated with increases in prosocial behaviors such as trust, altruism, generosity, cooperation and empathy. These various functions suggest that oxytocin may promote health by reducing stress and increasing calm/relaxed states, resulting in improved quality of life and well-being.
Given oxytocin’s stress-reducing and calming properties, and its capacity to increase well-being, its action may be relevant to those fighting cancer. We conducted a study to look at the effects of two mind-body therapies on changes in salivary oxytocin levels in a cancer survivor population with self-reported sleep disturbance. Investigating oxytocin in cancer survivors could be important, given cancer survivors’ high levels of distress, depression, and anxiety, as well as poor sleep, possibly due to the effects of cancer treatment and worries about cancer recurrence. In our study, we hypothesized that the mind-body therapies would increase oxytocin levels, which would be associated with improvements in sleep, increases in quality of life and well-being, and reduced stress. Read More